Invitrogen™ CKAP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531639

Catalog No. PIPA531639

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116, MDA-MB-231, aortic smooth muscle. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: CKAP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CKAP4
• Gene Alias: 5630400A09Rik; 63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; CKAP4; Climp-63; cytoskeleton associated protein 4; cytoskeleton-associated protein 4; ERGIC-63; LPC-1; p63; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10970
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.19 mg/mL
• Formulation: PBS with 20% glycerol; pH 7
• Gene Accession No.: Q07065
• Gene Symbols: CKAP4
• Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human CKAP4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov