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Invitrogen™ CKAP4 Polyclonal Antibody
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Catalog No. PIPA542926
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100 μL
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PIPA542926 100 μL
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Catalog No. PIPA542926 Supplier Invitrogen™ Supplier No. PA542926
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Description

Rabbit Polyclonal Antibody

Peptide sequence: SDGIHVVKDA RERDFTSLEN TVEERLTELT KSINDNIAIF TEVQKRSQKE Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CKAP4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CKAP4
Gene Accession No. Q07065
Gene Alias 5630400A09Rik; 63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; CKAP4; Climp-63; cytoskeleton associated protein 4; cytoskeleton-associated protein 4; ERGIC-63; LPC-1; p63; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63
Gene Symbols CKAP4
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human CKAP4.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10970
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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