Invitrogen™ CKAP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581924

Catalog No. PIPA581924

Description

Immunogen sequence: LKDLSDGIHV VKDARERDFT SLENTVEERL TELTKSINDN IAIFTEVQKR SQKEINDMKA KVASLEESEG NKQDLKALKE AVKEIQTSAK SREWDMEALR STLQTMES.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: CKAP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CKAP4
• Gene Alias: 5630400A09Rik; 63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; CKAP4; Climp-63; cytoskeleton associated protein 4; cytoskeleton-associated protein 4; ERGIC-63; LPC-1; p63; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10970
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q07065
• Gene Symbols: CKAP4
• Immunogen: Recombinant protein corresponding to Human CKAP4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG