Invitrogen™ CKMT2 Monoclonal Antibody (7B12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA532940

Catalog No. PIMA532940

Description

Purity is > 95% by SDS-PAGE.

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: CKMT2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P09605, P17540
• Gene Symbols: Ckmt2
• Immunogen: Recombinant full length Human CKMT2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 7B12
• Conjugate: Unconjugated
• Gene: Ckmt2
• Gene Alias: 2300008A19Rik; basic-type mitochondrial creatine kinase; CKMT2; Creatine kinase S-type, mitochondrial; creatine kinase, mitochondrial 2; creatine kinase, mitochondrial 2 (sarcomeric); creatine kinase, mitochondrial 2, sarcomeric; EC 2.7.3.2; mib-CK; sarcomeric mitochondrial creatine kinase; ScCKmit; SMTCK; S-MtCK
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1160, 688698
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid