Invitrogen™ CKMT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596097

Catalog No. PIPA596097

Description

Immunogen sequence: EVREQPRLFP PSADYPDLRK HNNCMAECLT PAIYAKLRNK VTPNGYTLDQ CIQTGVDNPG HPFIKTVGMV AGDEESYEVF ADLFDPVIKL RHNGYDPRVM KHTTDLDASK ITQGQFDEHY VLSSRVRTGR SIRGLSLPPA CTRAERREVE NVAITALEGL KGDLAGRYYK LSEMTEQDQQ RLIDDHFLFD K; Positive Samples: Mouse skeletal muscle, Mouse heart, Rat skeletal muscle; Cellular Location: Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein.

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: CKMT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ckmt2
• Gene Alias: 2300008A19Rik; basic-type mitochondrial creatine kinase; CKMT2; Creatine kinase S-type, mitochondrial; creatine kinase, mitochondrial 2; creatine kinase, mitochondrial 2 (sarcomeric); creatine kinase, mitochondrial 2, sarcomeric; EC 2.7.3.2; mib-CK; sarcomeric mitochondrial creatine kinase; ScCKmit; SMTCK; S-MtCK
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1160, 688698, 76722
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09605, P17540, Q6P8J7
• Gene Symbols: Ckmt2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_0018162).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG