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Invitrogen™ CKMT2 Polyclonal Antibody
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Catalog No. PIPA596925
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100 μL
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PIPA596925 100 μL
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Catalog No. PIPA596925 Supplier Invitrogen™ Supplier No. PA596925
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EVREQPRLFP PSADYPDLRK HNNCMAECLT PAIYAKLRNK VTPNGYTLDQ CIQTGVDNPG HPFIKTVGMV AGDEESYEVF ADLFDPVIKL RHNGYDPRVM KHTTDLDASK ITQGQFDEHY VLSSRVRTGR SIRGLSLPPA CTRAERREVE NVAITALEGL KGDLAGRYYK LSEMTEQDQQ RLIDDHFLFD K; Positive Samples: HeLa, Mouse skeletal muscle, Mouse heart, Mouse diaphragm, Rat skeletal muscle; Cellular Location: Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein.

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CKMT2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ckmt2
Gene Accession No. P09605, P17540, Q6P8J7
Gene Alias 2300008A19Rik; basic-type mitochondrial creatine kinase; CKMT2; Creatine kinase S-type, mitochondrial; creatine kinase, mitochondrial 2; creatine kinase, mitochondrial 2 (sarcomeric); creatine kinase, mitochondrial 2, sarcomeric; EC 2.7.3.2; mib-CK; sarcomeric mitochondrial creatine kinase; ScCKmit; SMTCK; S-MtCK
Gene Symbols Ckmt2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_0018162).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1160, 688698, 76722
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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