CLACP/COL25A1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-1544	100 μL

Catalog No. 50-198-1544 Supplier Bioss Supplier No. BS11643R

Description

Rabbit Polyclonal Antibody

Alzheimer’s disease (AD) is characterized by deposition of beta-amyloid as senile plaques and cerebral amyloid angiopathy. The principal component of AD amyloid is the amyloid beta peptide (A beta). Although production and deposition of A beta appear closely related to the pathogenesis of AD, current evidence suggest that A beta alone is not sufficient to cause neuronal death and symptoms of dementia. A component of senile plaque (SP), CLAC (collagen-like Alzheimer amyloid plaque component ) and its precursor CLAC-P are deposited with extracellular beta-amyloid and have been recently implicated in cell toxicity of beta-amyloid in AD brains. CLAC-P is a unique, membrane-bound collagen-like structure containing three Gly-X-Y repeat motifs and may define a novel class of neuronal collagens.

Specifications

• Antigen: CLACP/COL25A1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: COL25A1
• Gene Accession No.: Q9BXS0
• Gene Alias: 2700062B08Rik; Alzheimer disease amyloid-associated protein; AMY; CFEOM5; CLAC; CLACP; CLAC-P; COL25A1; Collagen alpha-1(XXV) chain; collagen type XXV alpha 1; collagen, type XXV, alpha 1; Collagen-like Alzheimer amyloid plaque component; collagenous Alzheimer amyloid plaque component; procollagen, type XXV, alpha 1
• Gene Symbols: COL25A1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human CLACP/COL25A1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 84570
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG