CLASP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8364	Proteintech Group Inc 129421AP150UL	150 μL

Description

CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Specifications

• Antigen: CLASP2
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O75122, Q8BRT1
• Gene ID (Entrez): 23122, 76499
• Immunogen: CLASP2 Fusion Protein Ag4012
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CLASP2

• Concentration: 0.23 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CLASP2, CLIP associating protein 2, hOrbit2, KIAA0627, Protein Orbit homolog 2
• Gene Symbols: Clasp2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody