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Invitrogen™ Claudin 14 Polyclonal Antibody
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Catalog No. 01674423
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500 μg
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Catalog No. Quantity
01-674-423 500 μg
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Catalog No. 01-674-423 Supplier Invitrogen™ Supplier No. PA19540
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Description

Chicken Polyclonal Antibody

PA1-9540 detects CLDN14 in human samples. PA1-9540 has been successfully used in Western blot procedures. By Western blot, PA1-9540 detects a 26 kDa protein representing CLDN14. PA1-9540 immunogen is a purified recombinant CLDN14 corresponding to the chromosome 21 gene (Human).

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Several transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 14
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CLDN14
Gene Accession No. O95500
Gene Alias AI851731; claudin 14; claudin-14; CLDN14; DFNB29; UNQ777/PRO1571
Gene Symbols CLDN14
Host Species Chicken
Immunogen Purified recombinant CLDN14 corresponding to the chromosome 21 gene (Human).
Purification Method IgY fraction
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23562
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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