Invitrogen™ Claudin 19 Monoclonal Antibody (693202)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524317

Catalog No. PIMA524317

Description

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].

Specifications

• Antigen: Claudin 19
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8N6F1
• Gene Symbols: CLDN19
• Immunogen: NS0 mouse myeloma cell line transfected with human Claudin-19.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: 693202
• Conjugate: Unconjugated
• Gene: CLDN19
• Gene Alias: claudin 19; claudin-19; Cldn19; HOMG5
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 149461
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized