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Invitrogen™ Claudin 19 Polyclonal Antibody
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Catalog No. FEPA5144714
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100 μL
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FEPA5144714 100 μL
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Catalog No. FEPA5144714 Supplier Invitrogen™ Supplier No. PA5144714
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GDAIITAVGL YEGLWMSCAS QSTGQVQCKL YDSLL Antigen sequence identity: Mouse 100%; Rat 100%.

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 19
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CLDN19
Gene Accession No. Q8N6F1
Gene Alias claudin 19; claudin-19; Cldn19; HOMG5
Gene Symbols CLDN19
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 37-71. Recombinant protein control fragment (Product #RP-109977).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149461
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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