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Invitrogen™ Claudin 19 Polyclonal Antibody
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Catalog No. PIPA5101526
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100 μL
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PIPA5101526 100 μL
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Catalog No. PIPA5101526 Supplier Invitrogen™ Supplier No. PA5101526
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CLDN19.

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 19
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CLDN19
Gene Accession No. Q5QT56, Q8N6F1
Gene Alias claudin 19; claudin-19; Cldn19; HOMG5
Gene Symbols CLDN19
Host Species Rabbit
Immunogen A synthesized peptide derived from human CLDN19(Accession Q8N6F1), corresponding to amino acid residues V85-T135.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149461, 298487
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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