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Invitrogen™ Claudin 22/24 Polyclonal Antibody
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Catalog No. PIPA5103747
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100 μL
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PIPA5103747 100 μL
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Catalog No. PIPA5103747 Supplier Invitrogen™ Supplier No. PA5103747
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CLDN22/24.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 22/24
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CLDN24
Gene Accession No. A6NM45, Q8N7P3
Gene Alias claudin 21; claudin 22; claudin 24; Claudin-21; Claudin-22; CLDN21; CLDN22; CLDN24; Putative claudin-24
Gene Symbols CLDN22, CLDN24
Host Species Rabbit
Immunogen A synthesized peptide derived from human CLDN22(Accession Q8N7P3), corresponding to amino acid residues L125-S175.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100132463, 306454, 502083, 53842
Target Species Human, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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