Invitrogen™ Claudin 6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA524205

Catalog No. PIPA524205

Description

This antibody is predicted to react with zebrafish based on sequence homology.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Specifications

• Antigen: Claudin 6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLDN6
• Gene Alias: AL024037; claudin 6; Claudin6; claudin-6; CLD6; CLDN6; Skullin; tight junction molecule claudin 6; UNQ757/PRO1488
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 54419, 9074
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P56747, Q9Z262
• Gene Symbols: CLDN6
• Immunogen: KLH conjugated synthetic peptide between 130-159 amino acids from the central region of human CLDN6.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov