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Invitrogen™ Claudin 6 Polyclonal Antibody
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Catalog No. PIPA5120728
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100 μL
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PIPA5120728 100 μL
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Catalog No. PIPA5120728 Supplier Invitrogen™ Supplier No. PA5120728
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Description

Rabbit Polyclonal Antibody

Positive test controls include: OVCAR3, Rat brain. Immunogen sequence: SGIVFVISGV LTLIPVCWTA HAIIRDFYNP LVAEAQKREL GASLYLGWAA SGLLLLGGGL LCCTCPSGGS QGPSHYMARY STSAPAISRG PSEYPTKNYV.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.76 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CLDN6
Gene Accession No. P56747, Q9Z262
Gene Alias AL024037; claudin 6; Claudin6; claudin-6; CLD6; CLDN6; Skullin; tight junction molecule claudin 6; UNQ757/PRO1488
Gene Symbols CLDN6
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 287098, 54419, 9074
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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