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Invitrogen™ Claudin 7 Polyclonal Antibody

Rabbit Polyclonal Antibody

$516.00 - $743.00

Specifications

Antigen Claudin 7
Concentration 0.12 mg/mL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
01-673-305
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Invitrogen™
PA137474
1 mL
Each for $743.00
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PIPA532356
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Invitrogen™
PA532356
500 μL
Each for $516.00
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Description

Description

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is colon carcinoma.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
Specifications

Specifications

Claudin 7
-20°C, Avoid Freeze/Thaw Cycles
Polyclonal
Liquid
IgG
Human, Mouse, Rat
CLDN7
CEPTRL2; claudin 7; claudin-1; Claudin-7; Cldn7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; Hs.84359
CLDN7
Primary
Antigen Affinity Chromatography
0.12 mg/mL
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
RUO
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
O95471, Q9Z1L1, Q9Z261
1366, 53624, 65132
Synthetic peptide from C-terminus of human claudin 7 protein.
Antibody
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