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Claudin 8 Recombinant Polyclonal Antibody (6HCLC), Invitrogen™

Catalog No. PI710223
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100 μg
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Catalog No. Quantity
PI710223 100 μg
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Catalog No. PI710223 Supplier Thermo Scientific Supplier No. 710223

Description

Rabbit Recombinant Polyclonal Antibody

This antibody is predicted to react with equine, mouse and rat based on sequence homology. Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Claudin-8 belongs to the claudin family of integral membrane proteins. Claudins are responsible for the formation of tight junction strands, and are connected with the actin cytoskeleton mediated by ZO-1. Claudin-8 is a tight junction protein expressed in several distal nephron segments, suggesting that it may have a role as a paracellular cation barrier protein. Claudin-8 is expressed in the inner ear, and the umbrella cell tight junctions in the bladder epithelium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 8
Applications Western Blot
Classification Recombinant Polyclonal
Clone 6HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene CLDN8
Gene Accession No. P56748
Gene Alias AI648025; claudin 8; claudin-8; CLDN8; epididymis secretory protein Li 79; HEL-S-79; UNQ779/PRO1573
Gene Symbols CLDN8
Host Species Rabbit
Immunogen Peptide corresponding to amino acids 206–225 of human claudin-8
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9073
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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