Invitrogen™ CLC-5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596402

Catalog No. PIPA596402

Description

Immunogen sequence: YPFLEAKEEF AHKTLAMDVM KPRRNDPLLT VLTQDSMTVE DVETIISETT YSGFPVVVSR ESQRLVGFVL RRDLIISIEN ARKKQDGVVS TSIIYFTEHS PPLPPYTPPT LKLRNILDLS PFTVTDLTPM EIVVDIFRKL GLRQCLVTHN GRLLGIITKK DVLKHIAQMA NQDPDSILFN; Positive Samples: SW480, U-937, HepG2, A673, NCI-H460, Mouse kidney, Mouse ovary, Mouse brain; Cellular Location: Cell membrane, Endosome membrane, Golgi apparatus membrane, Multi-pass membrane protein.

Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.

Specifications

• Antigen: CLC-5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLCN5
• Gene Alias: 5430408K11Rik; chloride channel 5; chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease); chloride channel ClC5; chloride channel Clc-5; chloride channel CLCN5; chloride channel protein 5; chloride channel, voltage-sensitive 5; chloride transporter ClC-5; chloride voltage-gated channel 5; Clc5; clC-5; CLCK2; CLCN3; CLCN4; Clcn5; D930009B12Rik; DENTS; DXImx42e; H(+)/Cl(-) exchange transporter 5; H(+)/Cl(-) exchange transporter 5-like; hCIC-K2; hClC-K2; NPHL1; NPHL2; Sfc13; T25545; voltage-gated chloride ion channel CLCN5; XLRH; XRN
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1184, 12728
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.09 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P51795, Q9WVD4
• Gene Symbols: CLCN5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 637-816 of human CLCN5 (NP_0011213701).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG