Invitrogen™ CLCC1 Polyclonal Antibody

Catalog No.	Quantity
PIPA552651	100 μL

Catalog No. PIPA552651 Supplier Invitrogen™ Supplier No. PA552651

Description

Rabbit Polyclonal Antibody

Immunogen sequence: PPQALRPRDR RRQEEIDYRP DGGAGDADFH YRGQMGPTEQ GPYAKTYEGR REILRERDVD LRFQTGNKSP EVLRAFDVPD AEAREHPTVV PSHKSPVLDT KPKE Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 64%.

Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation and memory deficiency. Neurofibromin has also been associated with the intermediated filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation and mutations of NF1 produce variable cell sizes and morphologies.

Specifications

• Antigen: CLCC1
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: CLCC1
• Gene Accession No.: Q96S66
• Gene Alias: chloride channel CLIC like 1; chloride channel CLIC-like 1; chloride channel CLIC-like protein 1; CLCC1; KIAA0761; MCLC; Mid-1-related chloride channel 1; mid-1-related chloride channel protein 1
• Gene Symbols: CLCC1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human CLCC1. Recombinant protein control fragment (Product #RP-90166).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23155
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG