Invitrogen™ CLCC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106642

Catalog No. PIPA5106642

Description

Antibody detects endogenous levels of total CLCC1.

Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation and memory deficiency. Neurofibromin has also been associated with the intermediated filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation and mutations of NF1 produce variable cell sizes and morphologies.

Specifications

• Antigen: CLCC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLCC1
• Gene Alias: chloride channel CLIC like 1; chloride channel CLIC-like 1; chloride channel CLIC-like protein 1; CLCC1; KIAA0761; MCLC; Mid-1-related chloride channel 1; mid-1-related chloride channel protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170927, 23155
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q96S66, Q9WU61
• Gene Symbols: CLCC1
• Immunogen: A synthesized peptide derived from human CLCC1(Accession Q96S66), corresponding to amino acid residues A396-D446.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG