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Invitrogen™ CLCC1 Polyclonal Antibody
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Catalog No. PIPA5120569
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100 μL
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PIPA5120569 100 μL
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Catalog No. PIPA5120569 Supplier Invitrogen™ Supplier No. PA5120569
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Description

Rabbit Polyclonal Antibody

Positive test controls include: U-87MG, 22Rv1, Mouse spleen. Immunogen sequence: GAGKSVHVLR HIGGPESEPP QALRPRDRRR QEEIDYRPDG GAGDADFHYR GQMGPTEQGP YAKTYEGRRE ILRERDVDLR FQTGNKSPEV LRAFDVPDAE AREHPTVVPS HKSPVLDTKP KETGGILGEG TPKESSTESS QSAKPVSGQD TSGNTEGSPA AEKAQLKSEA AGSPDQGSTY SPARGVAGPR GQDPVSSPCG.

Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation and memory deficiency. Neurofibromin has also been associated with the intermediated filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation and mutations of NF1 produce variable cell sizes and morphologies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLCC1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene CLCC1
Gene Accession No. Q96S66, Q99LI2
Gene Alias chloride channel CLIC like 1; chloride channel CLIC-like 1; chloride channel CLIC-like protein 1; CLCC1; KIAA0761; MCLC; Mid-1-related chloride channel 1; mid-1-related chloride channel protein 1
Gene Symbols CLCC1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 302-501 of human CLCC1 (NP_055942.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 229725, 23155
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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