CLCC1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA598800

Catalog No. PIPA598800

Description

Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation and memory deficiency. Neurofibromin has also been associated with the intermediated filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation and mutations of NF1 produce variable cell sizes and morphologies.

Specifications

• Antigen: CLCC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLCC1
• Gene Alias: chloride channel CLIC like 1; chloride channel CLIC-like 1; chloride channel CLIC-like protein 1; CLCC1; KIAA0761; MCLC; Mid-1-related chloride channel 1; mid-1-related chloride channel protein 1
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23155
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 4.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q96S66
• Gene Symbols: CLCC1
• Immunogen: Recombinant Human Chloride channel CLIC-like protein 1 protein (446-551AA)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG