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Invitrogen™ CLCN7 Polyclonal Antibody
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Catalog No. PIPA5101517
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100 μL
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PIPA5101517 100 μL
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Catalog No. PIPA5101517 Supplier Invitrogen™ Supplier No. PA5101517
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CLCN7.

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLCN7
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CLCN7
Gene Accession No. O70496, P51798, P51799
Gene Alias AA409691; AW538136; chloride channel 7; chloride channel 7 alpha subunit; Chloride channel protein 7; chloride channel, voltage-sensitive 7; chloride voltage-gated channel 7; CLC7; CLC-7; CLCN7; CLCN-7; D17Wsu51e; H(+)/Cl(-) exchange transporter 7; OPTA2; OPTB4; PPP1R63; protein phosphatase 1, regulatory subunit 63
Gene Symbols CLCN7
Host Species Rabbit
Immunogen A synthesized peptide derived from human CLCN7(Accession P51798), corresponding to amino acid residues M1-A40.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1186, 26373, 29233
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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