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CLCN7 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA560203
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PIPA560203 100 μL
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Catalog No. PIPA560203 Supplier Thermo Scientific Supplier No. PA560203

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LYDMHIQLQS VPFLHWEAPV TSHSLTAREV MSTPVTCLRR REKVGVIVDV LSDTASNHNG FPVVEHADDT QPARLQGLIL RSQLIVLLKH KVFVERS Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLCN7
Applications Immunocytochemistry, Immunohistochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CLCN7
Gene Accession No. P51798
Gene Alias AA409691; AW538136; chloride channel 7; chloride channel 7 alpha subunit; Chloride channel protein 7; chloride channel, voltage-sensitive 7; chloride voltage-gated channel 7; CLC7; CLC-7; CLCN7; CLCN-7; D17Wsu51e; H(+)/Cl(-) exchange transporter 7; OPTA2; OPTB4; PPP1R63; protein phosphatase 1, regulatory subunit 63
Gene Symbols CLCN7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CLCN7
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1186
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

Research Use Only

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