CLDN6 Monoclonal Antibody (OTI4B6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA506896

Catalog No. 50-167-6839

Description

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Specifications

• Antigen: CLDN6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P56747
• Gene Symbols: CLDN6
• Immunogen: Full length human recombit protein of human CLDN6 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI4B6
• Conjugate: Unconjugated
• Gene: CLDN6
• Gene Alias: claudin 6
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9074
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid