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Invitrogen™ CLEC14A Polyclonal Antibody
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Catalog No. PIPA547677
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100 μg
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PIPA547677 100 μg
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Catalog No. PIPA547677 Supplier Invitrogen™ Supplier No. PA547677
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Description

Sheep Polyclonal Antibody

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) CLEC1, rhCLEC2, rhCLEC3B, and rhCLEC10A is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLEC14A
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CLEC14A
Gene Accession No. Q86T13
Gene Alias 1200003C23Rik; AI642649; C14orf27; CEG1; Clec14a; ClECT and EGF-like domain containing protein; C-type lectin domain family 14 member A; C-type lectin domain family 14, member A; EGFR5; EGFR-5; Epidermal growth factor receptor 5; RGD1306232; UNQ236/PRO269
Gene Symbols CLEC14A
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant human CLEC14A Glu22-Ala397.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 161198
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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