Invitrogen™ CLEC14A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558798

Catalog No. PIPA558798

Description

Immunogen sequence: ARWDKLSGDV LCPCPGRYLR AGKCAELPNC LDDLGGFACE CATGFELGKD GRSCVTSGEG QPTLGGTGVP TRRPPATATS PVPQRTWPIR VDEKL Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 64%.

CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Specifications

• Antigen: CLEC14A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLEC14A
• Gene Alias: 1200003C23Rik; AI642649; C14orf27; CEG1; Clec14a; ClECT and EGF-like domain containing protein; C-type lectin domain family 14 member A; C-type lectin domain family 14, member A; EGFR5; EGFR-5; Epidermal growth factor receptor 5; RGD1306232; UNQ236/PRO269
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 161198
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86T13
• Gene Symbols: CLEC14A
• Immunogen: Recombinant protein corresponding to Human CLEC14A. Recombinant protein control fragment (Product #RP-99925).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG