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Invitrogen™ CLEC14A Polyclonal Antibody
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Catalog No. PIPA558798
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100 μL
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PIPA558798 100 μL
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Catalog No. PIPA558798 Supplier Invitrogen™ Supplier No. PA558798
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ARWDKLSGDV LCPCPGRYLR AGKCAELPNC LDDLGGFACE CATGFELGKD GRSCVTSGEG QPTLGGTGVP TRRPPATATS PVPQRTWPIR VDEKL Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 64%.

CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLEC14A
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CLEC14A
Gene Accession No. Q86T13
Gene Alias 1200003C23Rik; AI642649; C14orf27; CEG1; Clec14a; ClECT and EGF-like domain containing protein; C-type lectin domain family 14 member A; C-type lectin domain family 14, member A; EGFR5; EGFR-5; Epidermal growth factor receptor 5; RGD1306232; UNQ236/PRO269
Gene Symbols CLEC14A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CLEC14A. Recombinant protein control fragment (Product #RP-99925).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 161198
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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