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Invitrogen™ CLEC14A Recombinant Rabbit Monoclonal Antibody (036)
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Catalog No. PIMA531077
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100 μL
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PIMA531077 100 μL
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Catalog No. PIMA531077 Supplier Invitrogen™ Supplier No. MA531077
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Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse CLEC14A.

CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
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Specifications

Antigen CLEC14A
Applications ELISA
Classification Recombinant Monoclonal
Clone 036
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CLEC14A
Gene Accession No. Q8VCP9
Gene Alias 1200003C23Rik; AI642649; C14orf27; CEG1; Clec14a; ClECT and EGF-like domain containing protein; C-type lectin domain family 14 member A; C-type lectin domain family 14, member A; EGFR5; EGFR-5; Epidermal growth factor receptor 5; RGD1306232; UNQ236/PRO269
Gene Symbols CLEC14A
Host Species Rabbit
Immunogen Recombinant Mouse CLEC14A protein (Met1-Thr386).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66864
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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