Invitrogen™ CLEC2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534409

Catalog No. PIPA534409

Description

A suggested positive control is K562 cell lysate. PA5-34409 can be used with blocking peptide PEP-1451.

CLEC2A (C-type lectin domain family 2 member A), also known as PILAR (proliferation-induced lymphocyte-associated receptor) is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that contains one C-type lectin domain in its extracellular region and belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Manipulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer.

Specifications

• Antigen: CLEC2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLEC2A
• Gene Alias: CLEC2A; C-type lectin domain family 2 member A; C-type lectin domain family 2, member A; INPE5792; KACL; Keratinocyte-associated C-type lectin; PILAR; Proliferation-induced lymphocyte-associated receptor; UNQ579; UNQ5792; UNQ5792/PRO19597
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387836
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6UVW9
• Gene Symbols: CLEC2A
• Immunogen: A 16 amino acid synthetic peptide near the amino terminus of human CLEC2A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG