Invitrogen™ CLEC4E Monoclonal Antibody (WEN43)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA533341

Catalog No. PIMA533341

Description

Product is supplied at 1 mL (100 μL/mL). Application notes: Flow Cytometry - This anitbody stains the extracellular domain of Mincle transfected 293 cells. It does not bind to other receptors in the rat APLEC family. Functional Assay - This antibody can act complementary in the inhibition of phagocytosis. Positive control: BW5417 or 293T cells.

CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Specifications

• Antigen: CLEC4E
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: Q67EQ1
• Gene Symbols: CLEC4E
• Immunogen: Rat mincle-Fcgamma2b fusion protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Functional Assay
• Clone: WEN43
• Conjugate: Unconjugated
• Gene: CLEC4E
• Gene Alias: C86253; CLEC4E; CLECSF9; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9; C-type lectin domain family 4 member E; C-type lectin domain family 4, member E; C-type lectin superfamily member 9; C-type lectin, superfamily member 9; immunoreceptor; macrophage-inducible C-type lectin; Mincle; UNQ218/PRO244
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 450223
• Content And Storage: 4°C
• Form: Liquid