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CLEC4M, anti-Human, Clone: 16E7, Abnova™

Monoclonal Antibody

Manufacturer:  Abnova Corporation RAB00096

Catalog No. 89-032-439


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Specifications

Specifications

CLEC4M
16E7
Flow Cytometry (1 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
C-type lectin domain family 4, member M
CD209L|CD299|DC-SIGN2|DC-SIGNR|DCSIGNR|HP10347|L-SIGN|LSIGN|MGC129964|MGC47866
Original antibody is raised against human CD299.
200 μg
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Primary
10332
Human
Flow Cytometry, Immunohistochemistry
Unconjugated
In PBS, pH 7.2 (0.02% Proclin 300).
Liquid
CLEC4M
IgG, kappa
RUO
Antibody
Monoclonal
This antibody recognizes human CLEC4M, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
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