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CLEC4M, anti-Human, Clone: 16E7, Abnova™

Catalog No. 89032439 Shop All Abnova Corporation Products
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200 μg
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Catalog No. Quantity
89-032-439 200 μg
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Catalog No. 89-032-439 Supplier Abnova Corporation Supplier No. RAB00096
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Description

Monoclonal Antibody

Specifications

Antigen CLEC4M
Applications Flow Cytometry, Immunohistochemistry
Classification Monoclonal
Clone 16E7
Conjugate Unconjugated
Dilution Flow Cytometry (1 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.02% Proclin 300).
Gene C-type lectin domain family 4, member M
Gene Alias CD209L/CD299/DC-SIGN2/DC-SIGNR/DCSIGNR/HP10347/L-SIGN/LSIGN/MGC129964/MGC47866
Gene Symbols CLEC4M
Immunogen Original antibody is raised against human CD299.
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10332
Test Specificity This antibody recognizes human CLEC4M, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG κ
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