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Invitrogen™ CLEC5A Polyclonal Antibody
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Catalog No. PIPA547173
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100 μg
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Catalog No. Quantity
PIPA547173 100 μg
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Catalog No. PIPA547173 Supplier Invitrogen™ Supplier No. PA547173
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Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human MDL-1/CLEC5A is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLEC5A
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CLEC5A
Gene Accession No. Q9R007
Gene Alias CLEC5A; Clecsf5; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin domain family 5, member a; C-type lectin superfamily member 5; Ly100; Mdl1; MDL-1; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; type II transmembrane protein MDL-1
Gene Symbols CLEC5A
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse MDL-1/CLEC5A Tyr26-Lys190.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23845
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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