Invitrogen™ CLEC9A Monoclonal Antibody (700517)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA524319

Catalog No. PIMA524319

Description

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

C-type lectin domain family 9 member A (CLEC9A) is a gene located on chromosome 12p13.2, encoding a protein that belongs to the C-type lectin receptor family. CLEC9A is primarily expressed on dendritic cells and certain subsets of macrophages, playing a pivotal role in the immune system by recognizing and binding dead cell debris, including necrotic cells. This receptor facilitates the presentation of antigens derived from dead cells to T cells, thus contributing to the initiation of immune responses. CLEC9A is involved in cross-presentation, a process crucial for adaptive immunity, particularly in the context of viral infections and cancer. Its expression and activity are of particular interest for vaccine development and immunotherapy, given its ability to enhance antigen presentation and stimulate robust immune responses. Research into CLEC9A continues to explore its therapeutic potential for modulating immune activity in various diseases, including cancer and infectious diseases.

Specifications

• Antigen: CLEC9A
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8BRU4
• Gene Symbols: CLEC9A
• Immunogen: CHO-derived recombinant mouse CLEC9a Lys57-Ile264.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Frozen)
• Clone: 700517
• Conjugate: Unconjugated
• Gene: CLEC9A
• Gene Alias: 9830005G06Rik; CD370; Clec9a; C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; Dendritic cell natural killer lectin group receptor 1; DNGR1; DNGR-1; HEEE9341; RGD1562513; UNQ9341; UNQ9341/PRO34046
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 232414
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized