CLIC1 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 200401MP3

Catalog No. 50-199-0925

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human CLIC1. BLAST analysis was used to suggest cross-reactivity with CLIC1 from human sources based on 100% homology with the immunizing sequence, 98% homology with rat and mouse, and 97% homology with bovine and Oryctolagus cuniculus. Cross-reactivity with CLIC1 from other sources has not been determined.

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

Specifications

• Antigen: CLIC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLIC1
• Gene Alias: BOS_21623; Chloride channel ABP; chloride intracellular channel 1; Chloride intracellular channel protein 1; chloride intracellular channel protein 1 {ECO:0000250; Clcp; CLIC1; clic1 {ECO:0000312; DADB-110M10.1; EMBL:CAE83985.1, ECO:0000312; EMBL:CAE83985.1}; FLJ94671; G6; hRNCC; hypothetical protein LOC324481; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; Regulatory nuclear chloride ion channel protein; RGD:1303043}; RNCC protein; UniProtKB:O00299, ECO:0000312; wu:fc30e04; zgc:77044
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 1.06 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: O00299
• Gene Symbols: CLIC1
• Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with human CLIC1 recombinant protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 1192
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid