Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ CLIC5 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119978

Catalog No. PIPA5119978


Only null left
Add to Cart
This item is not returnable. View return policy

Description

Description

Positive Control: Human lung tissue lysates, mouse small intestine tissue. Subcellular Location: Cytoplasm, cytoskeleton, apical cell membrane, cell cortex, membrane; centrosome, golgi apparatus.

Clic5 encodes a protein that is required for normal hearing and is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. Clic5 can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Clic5 may play a role in the regulation of transepithelial ion absorption and secretion, and is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture. The Clic5 gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The protein encoded by Clic5 associates with actin-based cytoskeletal structures and may also play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for the Clic5 gene. Diseases associated with CLIC5 include Deafness, Autosomal Recessive 103 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CLIC5
Polyclonal
Unconjugated
CLIC5
5730531E12Rik; B330005L24; chloride channel protein; chloride channel protein p64; chloride intracellular channel 5; chloride intracellular channel protein 5; Chlorine channel protein p64; CLIC5; DFNB102; DFNB103; Gm322; jbg; MST130; MSTP130
Rabbit
Antigen affinity chromatography
RUO
224796, 53405
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Q8BXK9, Q9NZA1
CLIC5
Recombinant protein within human CLIC5 aa 41-240.
100 μL
Primary
Human, Mouse
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.