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Invitrogen™ CLIP1 Recombinant Rabbit Monoclonal Antibody (JE63-82)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA544803
This item is not returnable.
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Description
CLIP1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)
CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.
Specifications
CLIP1 | |
Recombinant Monoclonal | |
1 mg/mL | |
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
P30622 | |
CLIP1 | |
Synthetic peptide within human CLIP170 aa 1,389-1,438/1,438. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
JE63-82 | |
Unconjugated | |
CLIP1 | |
1110007I12Rik; 4631429H07Rik; AV017631; C81039; CAP-Gly domain containing linker protein 1; CAP-Gly domain-containing linker protein 1; CLIP; Clip 170; Clip1; CLIP170; CLIP-170; Clip50; Cyln1; cytoplasmic linker protein 1; Cytoplasmic linker protein 170; Cytoplasmic linker protein 170 alpha-2; cytoplasmic linker protein 50; cytoplasmic linker protein CLIP-170; Kiaa4046; MGC131604; mKIAA4046; Reed-Steinberg cell-espressed intermediate filament-associated protein; Reed-Sternberg intermediate filament-associated protein; Restin; restin (Reed-Steinberg cell-espressed intermediate filament-associated protein); restin (Reed-Steinberg cell-expressed intermediate filament-associated protein); Rsn | |
Rabbit | |
Protein A | |
RUO | |
6249 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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