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Invitrogen™ CLN6 Polyclonal Antibody
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Catalog No. PIPA584946
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100 μL
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PIPA584946 100 μL
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Catalog No. PIPA584946 Supplier Invitrogen™ Supplier No. PA584946
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LVFPLEWFPL NKPSVGDYFH MAYNVITPFL LLKLIERSPR TLPRSIT Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.

CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLN6
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CLN6
Gene Accession No. Q9NWW5
Gene Alias 1810065L06Rik; AW743417; ceroid-lipofuscinosis; ceroid-lipofuscinosis neuronal 6 late infantile; ceroid-lipofuscinosis neuronal protein 6; ceroid-lipofuscinosis, neuronal 6; ceroid-lipofuscinosis, neuronal 6, late infantile, variant; CLN4A; CLN6; D9Bwg1455e; HsT18960; nclf; neuronal ceroid lipofuscinosis; Protein CLN6
Gene Symbols CLN6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CLN6. Recombinant protein control fragment (Product #RP-107980).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54982
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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