CLN6 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-2825	150 μL

Catalog No. 50-173-2825 Supplier Proteintech Group Inc Supplier No. 203151AP150UL

Description

Rabbit Polyclonal Antibody

CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.

Specifications

• Antigen: CLN6
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.51 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: CLN6
• Gene Accession No.: Q9NWW5
• Gene Alias: CLN6, HsT18960, nclf, Protein CLN6
• Gene Symbols: CLN6
• Host Species: Rabbit
• Immunogen: CLN6 Fusion Protein Ag14159
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54982
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG