Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic Compounds
  5. Organoheterocyclic compounds
  6. Benzodiazepines
  7. Dibenzodiazepines
  8. Clozapine N-oxide, Tocris Bioscience™

Clozapine N-oxide, Tocris Bioscience™

Click to view available options
Quantity:
10mg
50mg
This item is not returnable. View return policy
34233-69-7
C18H19ClN4O
342.827
WYRDWWAASBTJLM-UHFFFAOYSA-N
clozapine n-oxide,clozapine-n-oxide,unii-mza8bk588j,chembl1688,mza8bk588j,n-oxyclozapine,clozapine n-oxide cno,oguczbiqsyywef-uhfffaoysa-n
2819
3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]
This item is not returnable. View return policy
34233-69-7
C18H19ClN4O
342.827
WYRDWWAASBTJLM-UHFFFAOYSA-N
clozapine n-oxide,clozapine-n-oxide,unii-mza8bk588j,chembl1688,mza8bk588j,n-oxyclozapine,clozapine n-oxide cno,oguczbiqsyywef-uhfffaoysa-n
2819
3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]

Description

Activator of muscarinic DREADDs

Metabolite of clozapine (Cat. No. 0444). Activates human muscarinic designer receptors (DREADDs) in vitro. Silences hippocampal neurons expressing hM4 DREADDs in vitro. Activates Gs-linked DREADDS- AgRP in mice via intracerebroventricular (i.c.v) injection. Shown to be a P-glycoprotein (P-gp) efflux pump substrate. Other potent and selective hM3Dq DREADD agonists available: DREADD agonist 21 and Perlapine .

Water soluble salt also available.

This product contains 1 molar equivalent of ethanol.

Quantity 50mg
Assay Percent Range >98%
Formula Weight 342.82
Percent Purity >99%
Chemical Name or Material Clozapine N-oxide

Safety and Handling

Recommended Storage : Store at Room Temperature