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  7. Clozapine, Tocris Bioscience™

Clozapine, Tocris Bioscience™

Catalog Number 0444500
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Quantity:
50 mg
500 mg
This item is not returnable. View return policy
5786-21-0
C18H19ClN4
326.828
ZUXABONWMNSFBN-UHFFFAOYSA-N
clozapine, leponex, clozapin, clozaril, fazaclo, clorazil, iprox, clozapinum, asaleptin, clozapina
2818
3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine
CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
This item is not returnable. View return policy
5786-21-0
C18H19ClN4
326.828
ZUXABONWMNSFBN-UHFFFAOYSA-N
clozapine, leponex, clozapin, clozaril, fazaclo, clorazil, iprox, clozapinum, asaleptin, clozapina
2818
3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine
CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl

Description

Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist

Clozapine is an atypical antipsychotic drug, with a much lower tendency to cause extrapyramidal side effects than conventional neuroleptics. Displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade (Ki values are 21, 170, 170, 230 and 330 nM for D4, D3, D1, D2 and D5 receptors respectively).
Quantity 500 mg
Formula Weight 326.83
Percent Purity >99%
Chemical Name or Material Clozapine

Safety and Handling

Recommended Storage Store at Room Temperature
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