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  5. Tocris Bioscience™ CLP 290

Tocris Bioscience™ CLP 290
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Catalog No. 675810
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10 mg
50 mg
Catalog No. Quantity
67-581-0 10 mg
67-585-0 50 mg
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Catalog No. 67-581-0

Supplier: Tocris Bioscience™ 6758/10

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Description

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

CLP 290 is a K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).

Specifications

Chemical Name or Material (Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2 H)-yl)thiazol-5(4 H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate
CAS 1181083-81-7
Quantity 10 mg
Target KCC2 Activators
Molecular Formula C19H21FN4O3S
Formula Weight 1990
Purity 98%
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