Tocris™ CLP 290

Catalog No. 67-585-0

Supplier: Tocris™ 6758/50

Description

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

CLP 290 is a K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).

Greener Choice Claims

• Environmental benefits include:
• Ozone-Safe or Safe for the Ozone Layer

Specifications

• Chemical Name or Material: (Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2 H)-yl)thiazol-5(4 H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate
• CAS: 1181083-81-7
• Quantity: 50 mg
• Target: KCC2 Activators
• Molecular Formula: C₁₉H₂₁FN₄O₃S
• Formula Weight: 7828
• Purity: 98%