Invitrogen™ CLPS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552699

Catalog No. PIPA552699

Description

Immunogen sequence: NLENGELCMN SAQCKSNCCQ HSSALGLARC TSMASENSEC SVKTLYGIYY KCPCERGLTC EGDKTIVGSI TNTNFGICHD AGR Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 72%.

The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CLPS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLPS
• Gene Alias: 2200003J09Rik; Clps; COL; Colipase; colipase, pancreatic; COLQ; pancreatic colipase preproprotein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1208
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P04118
• Gene Symbols: CLPS
• Immunogen: Recombinant protein corresponding to Human CLPS. Recombinant protein control fragment (Product #RP-90264).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG