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Invitrogen™ CLPS Polyclonal Antibody
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Catalog No. PIPA588748
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100 μL
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PIPA588748 100 μL
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Catalog No. PIPA588748 Supplier Invitrogen™ Supplier No. PA588748
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse pancreas, Rat pancreas Immunogen sequence: SVAYAAPGPR GIIINLENGE LCMNSAQCKS NCCQHSSALG LARCTSMASE NSECSVKTLY GIYYKCPCER GLTCEGDKTI VGSITNTNFG ICHDAGRSKQ.

The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLPS
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene CLPS
Gene Accession No. P04118, P17084, Q9CQC2
Gene Alias 2200003J09Rik; Clps; COL; Colipase; colipase, pancreatic; COLQ; pancreatic colipase preproprotein
Gene Symbols CLPS
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 13-112 of human CLPS (NP_0018231).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109791, 1208, 25680
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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