Invitrogen™ CMPK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA525130

Catalog No. PIPA525130

Description

CMPK2 Polyclonal Antibody for Western Blot, IHC (P), Flow

UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response.

Specifications

• Antigen: CMPK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CMPK2
• Gene Alias: 1200004E04Rik; Cmpk2; cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; cytidine/uridine monophosphate kinase 2; cytidylate kinase 2; mitochondrial UMP-CMP kinase; NDK; Nucleoside-diphosphate kinase; TDKI; thymidine monophosphate kinase 2; thymidylate kinase family LPS-inducible member; thymidylate kinase homologue; thymidylate kinase LPS-inducible member; TMPK2; Tyki; UMP/CMP kinase; UMP-CMP kinase 2, mitochondrial; UMP-CMPK2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 129607
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q5EBM0
• Gene Symbols: CMPK2
• Immunogen: KLH conjugated synthetic peptide between 142-170 amino acids from the central region of human CMPK2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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