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CMRF-56 Mouse, anti-Human, R718, Clone: CMRF-56, BD OptiBuild™

Catalog No. BDB751896 Shop All BD Biosciences Products
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BDB751896 50 μg
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Catalog No. BDB751896 Supplier BD Biosciences Supplier No. 751896
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Description

Mouse Monoclonal Antibody

The CMRF-56 monoclonal antibody specifically binds to a 96 kDa, early activation/differentiation antigen expressed on dendritic cells (DCs). The CMRF-56 antigen is expressed on isolated Langerhans cells, dermal DCs, migratory dermal DCs and monocyte derived DCs (GM-CSF, IL-4, TNF-α). Circulating blood DCs are CMRF-56-, but its expression is induced within 6 hrs of in vitro culture. Tonsil and synovial fluid DCs upregulate CMRF-56 expression following short-term in vitro culture. It is not detected on resting peripheral blood leukocytes, but is on a subpopulation of tonsil B cells and on in vitro cultured CD19+ cells. CMRF-56 was generated using the Hodgkin's-derived L428 cell line as immunogen. This reagent could be useful in flow cytometric or immunomagnetic separation procedures and immunohistochemical staining of acetone-fixed frozen tissue sections.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CMRF-56
Applications Flow Cytometry
Classification Monoclonal
Clone CMRF-56
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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