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Invitrogen™ CMYA5 Polyclonal Antibody
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Catalog No. PIPA5139923
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100 μL
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PIPA5139923 100 μL
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Catalog No. PIPA5139923 Supplier Invitrogen™ Supplier No. PA5139923
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: SDVPKQSVLV SKHHLEAAED TRVKEPLSSA KSNYAQFISN TSASNADKMV SNKEMPKEPE DTYAKGEDFT VTSKPAGLS Highest antigen sequence indentity to the following orthologs: Mouse - 54%, Rat - 58%.

SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CMYA5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CMYA5
Gene Accession No. Q8N3K9
Gene Alias 2310076E16Rik; 2310076E21Rik; AA420382; AI504003; C5orf10; cardiomyopathy associated 5; cardiomyopathy-associated protein 5; CMYA5; DTNBP2; Dystrobrevin-binding protein 2; genethonin-3; heart and skeletal muscle-specific and sprouty domain-containing; myospryn; SPRY domain-containing protein 2; SPRYD2; sr553; Srfsd; stretch response protein 553; stretch-response protein 553; stretch-responsive fibronectin protein type 3; Tims; TRIM76; TRIM-like protein; tripartite motif-containing 76; tripartite motif-containing protein 76
Gene Symbols CMYA5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CMYA5. Recombinant protein control fragment (Product #RP-109385).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 202333
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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