Invitrogen™ CNDP2 Monoclonal Antibody (OTI8A2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525611

Catalog No. PIMA525611

Description

CNDP2 Monoclonal Antibody for Western Blot, IHC (P), Flow

The CNDP2 gene encodes the protein carnosine dipeptidase 2, which belongs to the M20 metallopeptidase family and plays a critical role in the metabolism of dipeptides. CNDP2 is primarily involved in the hydrolysis of carnosine, a dipeptide composed of beta-alanine and histidine, and is expressed in various tissues, including the liver and kidney. This enzyme is significant in cellular processes related to nitrogen metabolism and the regulation of histidine-containing dipeptides, which have antioxidant properties influencing cellular redox balance. CNDP2 has implications in renal function and disease, where altered activity can impact the concentration of bioactive peptides involved in protective mechanisms against oxidative stress. Additionally, CNDP2 may have roles in metabolic diseases, such as diabetes and hypertension, where dipeptide regulation can influence metabolic pathways and cellular protection mechanisms. Ongoing research explores CNDP2's enzymatic activity, regulation, and potential therapeutic applications, particularly in conditions where modulation of peptide metabolism can offer clinical benefits.

Specifications

• Antigen: CNDP2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96KP4
• Gene Symbols: Cndp2
• Immunogen: Full length human recombinant protein of CNDP2 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI8A2
• Conjugate: Unconjugated
• Gene: Cndp2
• Gene Alias: 0610010E05Rik; C76600; carnosine dipeptidase 2; carnosine dipeptidase II; CN2; CNDP dipeptidase 2; CNDP dipeptidase 2 (metallopeptidase M20 family); Cndp2; CPGL; cytosolic nonspecific dipeptidase; Cytosolic non-specific dipeptidase; cytosolic nonspecific dipeptidase 2; Dip-2; Epididymis secretory protein Li 13; glutamate carboxypeptidase-like protein 1; HEL-S-13; HsT2298; Pep1; Pep-1; PEPA; peptidase 1; peptidase A; wu:fd20d11; wu:fe17f09; zgc:92569
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55748
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid