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Invitrogen™ CNDP2 Polyclonal Antibody
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Catalog No. PIPA583357
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100 μL
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PIPA583357 100 μL
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Catalog No. PIPA583357 Supplier Invitrogen™ Supplier No. PA583357
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AKWVAIQSVS AWPEKRGEIR RMMEVAAADV KQLGGSVELV DIGKQKLPDG SEIPLPPILL GRLGSDPQKK TVCI Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 95%.

The CNDP2 gene encodes the protein carnosine dipeptidase 2, which belongs to the M20 metallopeptidase family and plays a critical role in the metabolism of dipeptides. CNDP2 is primarily involved in the hydrolysis of carnosine, a dipeptide composed of beta-alanine and histidine, and is expressed in various tissues, including the liver and kidney. This enzyme is significant in cellular processes related to nitrogen metabolism and the regulation of histidine-containing dipeptides, which have antioxidant properties influencing cellular redox balance. CNDP2 has implications in renal function and disease, where altered activity can impact the concentration of bioactive peptides involved in protective mechanisms against oxidative stress. Additionally, CNDP2 may have roles in metabolic diseases, such as diabetes and hypertension, where dipeptide regulation can influence metabolic pathways and cellular protection mechanisms. Ongoing research explores CNDP2's enzymatic activity, regulation, and potential therapeutic applications, particularly in conditions where modulation of peptide metabolism can offer clinical benefits.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNDP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cndp2
Gene Accession No. Q96KP4
Gene Alias 0610010E05Rik; C76600; carnosine dipeptidase 2; carnosine dipeptidase II; CN2; CNDP dipeptidase 2; CNDP dipeptidase 2 (metallopeptidase M20 family); Cndp2; CPGL; cytosolic nonspecific dipeptidase; Cytosolic non-specific dipeptidase; cytosolic nonspecific dipeptidase 2; Dip-2; Epididymis secretory protein Li 13; glutamate carboxypeptidase-like protein 1; HEL-S-13; HsT2298; Pep1; Pep-1; PEPA; peptidase 1; peptidase A; wu:fd20d11; wu:fe17f09; zgc:92569
Gene Symbols Cndp2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CNDP2. Recombinant protein control fragment (Product #RP-102752).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55748
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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