Invitrogen™ CNDP2 Recombinant Rabbit Monoclonal Antibody (001)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA529689

Catalog No. PIMA529689

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse CNDP2.

The CNDP2 gene encodes the protein carnosine dipeptidase 2, which belongs to the M20 metallopeptidase family and plays a critical role in the metabolism of dipeptides. CNDP2 is primarily involved in the hydrolysis of carnosine, a dipeptide composed of beta-alanine and histidine, and is expressed in various tissues, including the liver and kidney. This enzyme is significant in cellular processes related to nitrogen metabolism and the regulation of histidine-containing dipeptides, which have antioxidant properties influencing cellular redox balance. CNDP2 has implications in renal function and disease, where altered activity can impact the concentration of bioactive peptides involved in protective mechanisms against oxidative stress. Additionally, CNDP2 may have roles in metabolic diseases, such as diabetes and hypertension, where dipeptide regulation can influence metabolic pathways and cellular protection mechanisms. Ongoing research explores CNDP2's enzymatic activity, regulation, and potential therapeutic applications, particularly in conditions where modulation of peptide metabolism can offer clinical benefits.

Specifications

• Antigen: CNDP2
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: Cndp2
• Gene Alias: 0610010E05Rik; C76600; carnosine dipeptidase 2; carnosine dipeptidase II; CN2; CNDP dipeptidase 2; CNDP dipeptidase 2 (metallopeptidase M20 family); Cndp2; CPGL; cytosolic nonspecific dipeptidase; Cytosolic non-specific dipeptidase; cytosolic nonspecific dipeptidase 2; Dip-2; Epididymis secretory protein Li 13; glutamate carboxypeptidase-like protein 1; HEL-S-13; HsT2298; Pep1; Pep-1; PEPA; peptidase 1; peptidase A; wu:fd20d11; wu:fe17f09; zgc:92569
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 66054
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 001
• Formulation: PBS with no preservative
• Gene Accession No.: Q9D1A2
• Gene Symbols: Cndp2
• Immunogen: Recombinant Mouse CNDP2 protein (Met1-Asn475).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG